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Meridia affects chemicals in the body that are related to weight maintenance and reduction.

Meridia is used together with diet and exercise to treat obesity that may be related to diabetes mellitus, high cholesterol, or high blood pressure.

Meridia may also be indicated for other purposes not listed in this medication guide.

Do not use Meridia if you have taking other MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) in the last 14 days. Serious, life threatening adverse effects can occur if you use Meridia before the MAO inhibitor has cleared from your body. You should not take sibutramine if you are allergic to it, or if you have severe or uncontrolled high blood pressure, an eating disorder), or if you are taking stimulant diet pills.

Before taking this drug, tell your doctor if you have glaucoma, high blood pressure, heart disease, a history of heart attack or stroke, liver or kidney disease, depression, underactive thyroid, seizures, a bleeding disorder, a history of gallstones, or if you are older than 65 or younger than 16.

Tell your physician about all prescription and over-the-counter medications you use, especially antidepressants, narcotic pain medicine, or migraine headache medicines.

Tell your health care provider if you do not lose at least 4 pounds after taking the medication for 4 weeks along with a low calorie diet. This drug belongs to FDA pregnancy category C and it is not proven whether Meridia is harmful to an unborn baby. Before taking this drug, tell your doctor if you plan to get pregnant. Use effective birth control while taking this drug, and tell your doctor if you become pregnant during administering treatment. It is not known whether sibutramine passes into breast milk or if it could cause harm a nursing baby. Do not use this medication without telling your physician you are breast-feeding a baby. Do not give this drug to anyone younger than 16 years old.